Search on: HISTIOCYTOSIS, LANGERHANS-CELL 
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Descriptor English:   Histiocytosis, Langerhans-Cell 
Descriptor Spanish:   Histiocitosis de Células de Langerhans 
Descriptor Portuguese:   Histiocitose de Células de Langerhans 
Synonyms English:   Histiocytosis X
Langerhans-Cell Granulomatosis
Langerhans-Cell Histiocytosis  
Tree Number:   C08.381.483.375
C15.604.250.400
Definition English:   A group of disorders resulting from the abnormal proliferation of and tissue infiltration by LANGERHANS CELLS which can be detected by their characteristic Birbeck granules (X bodies), or by monoclonal antibody staining for their surface CD1 ANTIGENS. Langerhans-cell granulomatosis can involve a single organ, or can be a systemic disorder. 
History Note English:   90(75); was see under RETICULOENDOTHELIOSIS 1966-75; was HISTIOCYTOSIS X 1975-89 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DH diet therapy
DT drug therapy EC economics
EM embryology EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RA radiography
RI radionuclide imaging RT radiotherapy
RH rehabilitation SU surgery
TH therapy US ultrasonography
UR urine VE veterinary
VI virology  
Record Number:   28223 
Unique Identifier:   D006646 

Occurrence in VHL:
 

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